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Pseudomonas aeruginosa

- Discussion:
    - may cause often fatal bacteremia common due to localized infections following surgery or burns;
    - may cause post burn sepsis, bacteremia, septicemia, otitis media, meningitis, pneumonia, and other infections;
    - is the predominant infecting organism in deep puncture wounds of the foot (see foot infections);
    - it is the only gram negative bacillus which produces a glycocalyx;
    - source: widely distributed in nature; hospital environment;
    - may be normal flora in 5% of the population;
    - microscopy reveals gm neg rods in singles;

- Antipseudomonal Antibiotics:
    - carbenicillin
    - ticarcillin / timentin
    - mezlocillin
    - azlocillin
    - piperacillin
    - ceftazidime
    - ciprofloxacin
    - imipenem
    - norfloxacin
    - ofloxacin
    - tobramycin
    - ceph 3
    - polymyxin
    - aztreom
    - sulfamylon

Oral ciprofloxacin compared with parenteral antibiotics in the treatment of osteomyelitis.

Oral ciprofloxacin treatment of Pseudomonas aeruginosa osteomyelitis.

Management of Pseudomonas osteochondritis complicating puncture wounds of the foot

Source of Pseudomonas in osteomyelitis of heels.

Complications of deep puncture wounds of the foot.

Pseudomonas aeruginosa biofilm formation and slime excretion on antibiotic-loaded bone cement.

In vitro efficacy of ciprofloxacin and gentamicin against a biofilm of Pseudomonas aeruginosa and its free-living forms.

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