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Medications

Wheeless’ Textbook of Orthopaedics – Ortho Links

Anyone interested in posting orthopaedic educational links should send e-mail to: crwmd@msn.com Orthopaedic Links Page Orthopaedic Network Slack Inc. Orthopaedic Mailing List Doctor’s Guide to the Internet Prosthetic Research Study American Academy of Orthopaedic Surgeons TraumaNet Ruth Jackson Orthopaedic Society: Southern California Orthopedic Institute: University of Texas Southwestern, Department of Orthopaedics University of Washington Department … Read more

Wheeless’ Textbook of Orthopaedics

About the Author Disclaimer:   This textbook was derived from a variety of sources, including journal articles,   national meetings, lectures, and other textbooks.   Under no circumstances should   this material supervene the clinical judgment of the physician nor should this   material supervene any published data regarding critical care managment or   drug … Read more

WBC Differential

    – See Neutrophils/Left Shift  – Lymphocytes: (24-44%)  – Increased: Measles, German Measles, Mumps, Whooping Cough, Small pox, Chicken pox, Influenza, Hepatitis, Infectious Mononucleosis, Acute Infectious Lymphocytosis in children, Virtually any Viral Infection, Acute and Chronic Lymphocytic Leukemias;  – Decreased: After Stress, Burns, Trauma, Nl variation, Uremia;  – Monocytes (3-7%)  – Increased: Bacterial infection … Read more

Warfarin Interactions and Resistance

– Contraindications same as Heparin:  – ASA (Bleeding)  – w/ hemorrhagic tendencies  – pregnancy  – severe hepatic or renal disease  – severe hypertension  – blood dyscrasis  – Agents which Increase Prothrombin Time:  – Acetaminophren;  – Allopurinol  – ASA – Steroids  – Cimetidine – Indomethacin  – Flaggyl  – Hypoglycemics  – Phenothiazines – Phenylbutazone  – Propylthiouracil  – … Read more

Vertebral Osteomyelitis

– See:        – Diskitis        – Gun Shot Wounds to the Spine        – Tuberculous Spondylitis – Discussion:     – in adults, lumbar infections may often originate from urinary tract infections which drain thru Batson’s venous plexus;           – respiratory system is also … Read more

Vancomycin

– Discussion:      – for penicillin resistant to staph – MSSA / MRSA – and w/ enterococci endocarditis (in combination with aminoglycosides);     – it is ineffective against gm neg bacterial (its large molecular weight keeps it from penetrating the outer cell membrane of            gram-negative bacilli);     – basic science:            – blocks glycopeptide polymerization in … Read more

Urinary Tract Infection

– UTI in the Spine Injured Patient  Management:    – Rx with ATB’s, pending urine culture    – Consider single dose therapy for symptomatic non-pregnant women with no known anatomic abnormalities;    – Follow up culture in 7 to 14 days;    – Prolonged therapy (7-10 days) is for symptomatic men, pregnant women or patients with … Read more

Tuberculosis

– Discussion: – although the disease is generally more likely to be chronic, acute mycobacterial arthritis has been reported; – periarticular bone lesions may accompany the synovial involvement; – pulmonary tuberculosis is evident in only half the patients with skeletal involvement; – pulmonary TB signs vary with stage of dz, few early on; – later … Read more

Trimethoprim-Sulfamethoxazole/Bactrim/Septra

– Discussion:     – for UTI, otitis media, acut exacerbation of chronic bronchitis, pneumocystis carini;     – has an excellent spectrum of activity against beta lactamase-producing staph, and can be effective as an antistaphylococcal agent;     – septra not effective vs. group A strep;     – adult dose:       … Read more