Histological Features of Giant Cell Tumor of Bone
– Discussion: – numerous multinucleated giant cells, proliferative stroma, areas of necrosis, reactive peripheral bone, & occassional mitotic figures in the stroma (but no mitotic figures in the giant cells); – stromal cells appear elongate with oval nuclei; – giant cells may resemble osteoclasts; – Histologic Differential Dx: … Read more
