– See: – Bone Tumor Menu and Osteosarcoma Demonstration Project – Discussion: – malignant tumor of bone in which neoplastic osteoid is produced by a proliferating spindle cell stroma; – most common primary malignant bone tumor of mesenchymal derivation; – arises in adolescents, and second or third decade; – … Read more
– for PUD, prophylaxis in trauma, burns, surgery; – Adult: active PUD: 300 mg PO/IV tid-qid, or 400 mg PO bid; – over 90% of ulcers should heal after 12 wks of therapy – Hosp Prac. 1979 – ulcers which have not healed after 12 wks, probably will not heal w/ H2 Blockers; – for … Read more
– See: Bone Tumor Menu – Discussion: – malignant cartilaginous tumor of bone (3rd most common malignant bone tumor / comprises 20% of malignant bone lesions); – it is less common and less aggressive than osteosarcoma; – staging: – histologic grading is best predictor of stage; – most often presents as … Read more
– Indications: – long acting thiazide like diuretic used in hypertension; – edema associated w/ CHF, cirrhosis, steroid and estrogen therapy; – Adult: 50-100mg POqd; – Contraindications: allergy to sulfa drugs; – Caution with patients w/ impaired hepatic or renal function or SLE; – Peds: 2mg/kg/dose PO 3 times a week
– for insomnia, used as a sedatvie especially in children; also use as preoperative sedative; sedative hypnotic, non barbiturate; – Adult: 500mg-1gm PO or PR qhs prn (max 2gm/day); – Causes gastric and mucosal irritation; – Contraindicated with marked hepatic or renal impairment, or with severe cardiac disease; – Use with caution w/concomitant oral anticoagulant use … Read more
– See: Skin Prep – Discussion: (chloroprep) – kills cells by disrupting their cell membranes and precipitating cell contents; – it has extremely low toxicity even when used on the intact skin of new borns; – in comparison to alcohols, antibacterial activity of chlorohexidine gluconate is not as rapid, but the drug remains … Read more
– See: Anesthesia Considerations and Timing – PreOp Management: – Etiology of Fracture: – arrhythmia: consider continuous monitoring – hypoxia – osteoporosis – pathologic hip fractures – seizure – stroke – … Read more
– Discussion: – for mild pain, inflamation, RA, and prevention of stroke and DVT; – dosage: – adult: w/ pain and fever: 325-650mg q4hr PO, PR; – rhuematoid arthritis: 3-12gm/day; – check serum levels, therapeutic = 20-30 mg/dl; … Read more
– See: – Knee Joint Menu: – Chondral and Osteochondral Injuries of the Knee and Meniscal Tears – Discussion: – arthroscopic lavage alone may be of some benefit; – debridement has little value for long-standing or severe osteoarthritis of knee – where as, in the recent … Read more
– Discussion: – serves as screening test for collagen vascular dz and lupus; – fluorescent antinu-clear antibody test: (FANA) – indirect immunofluorescence assay is the initial screening test used to detect ANAs; – testing for specific auto-antibodies: – if … Read more