- See:
- osteoblasts and osteoclasts
- Discussion:
- osteocyte is mentioned as possibly having resorptive capabilities;
- it is the most numerous type of bone cell and is derived from an osteoblasts that is not longer synthesizing collagen;
- osteocytes were once considered to be dormant, metabolically inactive cells;
- this is now evidence that they can synthesize collagen, control bone mineralization within their lacunae, and possibly carry out bone resorption;
- resorption:
- when exposed to parathyroid hormone, osteocytes can secrete enzymes which begin to disolve the osteoid;
- w/ hyperparathyroidism, Pagets disease, or disuse osteoporosis, osteocytes may be involved in the excessive bone resorption