- Discussion: 
- Nicardipine is a calcium channel blocker related to nifedipine;

- Dosing Information: 
- Initial doses of immediate release nicardipine are 20 mg PO TID with dose titrations to 40 mg PO TID at 2 week intervals; 
- Sustained release dosing begins with 30 mg BID
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Controlled multicenter double-blind trial of nicardipine in the treatment of primary Raynaud phenomenon. French Cooperative Multicenter Group for Raynaud Phenomenon, Paris, France.