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Lactic Acidosis

- See: Metabolic Acidosis 

- Discussion:
    - develops during shock when there is inadequate cellular perfusion & cellular hypoxia;
    - caused by accumulation of lactate and hydrogen ions (protons), but extent of acidosis, as defined by pH, and the concentration of lactate required
                    for diagnosis of lactic acidosis is controversial;
    - blood or plasma lactate concentration normally ranges from 0.5-1.5 mmol/L

Scoring systems and blood lactate concentrations in relation to the development of adult respiratory distress syndrome and multiple organ failure in severely traumatized patients.

Serum lactate as a marker of mortality in patients with hip fracture: A prospective study.

Review Article. Lactic Acidosis