- See: Ossification of Soft Tissue and Periosteum:
- Discussion:
- heritable dz characterized by periarticular metastatic calcification;
- typically the shoulders and hips are affected most often;
- vascular and visceral calcification does not occur;
- hyperphosphatemia may play a role in this disorder;
- Clincal Presentation:
- affects blacks w/ positive family history, most often;
- disease manifests before age 20 years;
- tend to have multiple lesions;
- soft tissue tumors of ectopic calcification are usually painless and grow at variable rates;
- masses may be hard and may attached to the deep fascia;
- since the deposits are extracapsular, joint ROM is not impaired;
- Lab:
- hyperPhosphatemia and increased serum calcitriol levels are present in some patients;
- X-ray:
- densely calcified lobules that are confined to soft tissues;
- radiographically these masses are similar to those seen in renal failure