- Discussion:
- quantitative CT is unique in that it can determine both bone density and distribution in three dimensions at any skeletal site;
- bone density can be estimated separately in trabecular and cortical bone compartments;
- generally performed at the lumbar spine using routine CT scanners;
- quantitive CT has the best sensitivity and specificity for distinguishing patients with spinal osteoporosis from subjects without it;
- after QCT, most specific and sensitive tests are DXA and dpa, and finally SPA