Discussion JRA is a persistent non infectious arthritis lasting more than 6 wks to 3 months after other possible etiologies have bee ruled out; most common chronic childhood rheumatoid dz; affects girls more than boys; synovial proliferation leads to joint destruction (chondrolysis) & soft tissue destruction; severe joint destruction is seen in only 5% of … Read more
General Discussion of Synovial Fluid (see also: glycosaminoglycans and proteoglycans; friction and lubrication) synovial fluid is an ultrafiltrate of blood plasma plus hyaluronic acid and glycoproteins; synovial fluid resembles material in interstices of loose connective tissue in respect to both components; rate and method of passage of substances into & out of synovial fluid depend … Read more
(see also: Spondyloarthropathies) Discussion affects young men (ages 15 to 25 years), but may also begin in middle-aged men; disease is often more severe when it occurs early in life; disease characterized by insidious onset of pain and stiffness in lower back associated w/ gradual loss of spinal mobility; illness may cause inflammation in uveal tract … Read more