Home » Orthopaedics » Rx of Hypernatremia Rx of Hypernatremia July 22, 2020 by Data Trace Editor - See: - Diff Dx: - Diff Dx: - may result from spinal fusion; - most often results from ECF volume depletion due to hypotonic fluid loss (Vomiting, Diarrhea, Sweating, Osmotic diuress)