Home » Ortho Related » Medications » PHYSOSTIGMINE/ANTILIRIUM PHYSOSTIGMINE/ANTILIRIUM September 26, 2020July 22, 2020 by Data Trace Editor Antidote for tricyclic antidepressent, atropine, scopolamine overdose; reversible anticholinesterase; Adult: .5-2mg IV slowly; 1mg SQ q15min; Note rapid IV administration associated with convulsions; cholinergic side effects; may cause asystole