Home » Ortho Related » Medications » NALBUPHINE/NUBAIN NALBUPHINE/NUBAIN July 22, 2020 by Data Trace Editor for moderate to severe pain; Synthetic partial opiate agonist/antagonist; Adult: 10-20mg IM, IV, SQ; q4-6hr prn; Causes CNS depression and drowsiness; use with caution in patients receiving opiate drugs; KEY PAIN OPIOID