Aspartate Aminotransaminase (AST): Increased: Acute MI Liver dz Reye's syndrome Muscle Trauma / Injection / Polymyositis Pancreatitis Intestinal Injury or Surgery, Factitious Increase (Erythromycin, Opitates) Burns, Cardiac catheterization Brain Damage Renal Infarction TPN Glutamic Pyruvic Transaminase (SGPT) 8-50 U/L; Alanine Aminotransaminase (ALT)
- SGPT is more elevated t(an SGOT in Viral Hepatitis; SGOT is elevated more than SGPT in ETOH hepatitis;
- w/ decr LFT & incrg Bili/PT = Sever damage;
- Uremia may lead to false low AminoTransferase;
- Increased: Liver dz, Liver metastasis Bilary obstruction, Pancreatitis Liver congestion TPN