Home » Ortho Related » Medications » Doxepin/Sinequan Doxepin/Sinequan September 27, 2020July 22, 2020 by Data Trace Editor - Tricyclic Antidepressant; - Usual daily dose: 75-300 mg/day; - Note Side Effects: Sedation: +++;Insomnia: 0; Anticholinergic: ++; Orthostatic-Hypotension: +++; Nausea: 0