Home » Ortho Related » Medications » Bisoprolol fumarate and Hydrochlorothiazide / Ziac Bisoprolol fumarate and Hydrochlorothiazide / Ziac September 16, 2020July 22, 2020 by Data Trace Editor - Discussion: - antihypertensive agent which contains a beta blocker and a diuretic; - initial dosing should start at: 2.5 / 6.25 mg tablet, and 5.0 mg / 6.25 mg tab qd is a common maintenance dose; - max dose: 20/12.5 mg (two 10/6.25 mg tablets) qd