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- Total: <0.2-1.0 mg/dL; Direct: <0.2 mg/dL; Indirect: <0.8 mg/dL Increased Total: Hepatic damage (Hepatitis, Toxins, Cirrhosis), Bililary Obstruction (stone or tumor), Hemolysis, Fasting; Increased Direct (Conjugated): Biliary obstruction/cholestasis (gallstone, tumor, stricture), Med induced Cholestasis, Dubin Johnson and Rotor's syndrome; Increased Indirect (Unconjugated): "Hemolytic jaundice" from Transfusion RXN, HbS ect.; Gilbert's dz, Crigler Najjar syndrome