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Dantrolene Na/Dantrium

- Discussion:
    - for treatment of clinical spasticity resulting from upper motor neuron disorders such as spinal cord injuries, strokes, cerebral palsy, or multiple sclerosis;
    - treatment of Malignant Hyperthermia crisis; is a skeletal muscle relaxant;
    - skeletal muscle relaxant: beginning at 25 mg PO qd, titrate to effect by 25 mg up to max dose of 100 mg PO qid prn;
    - monitor LFT's (ALT, AST) closely;
    - peds: Initially 0.5 mg/kg bid, titrate by 0.5 mg/kg to effectiveness up to max dose of 3 mg/kg qid prn