- Discussion:
- bone marrow signal on T1- and T2 vary with age
- in adults, tumor invading bone marrow will show decreased signal on T1, in contrast to normally high signal-intensity bone marrow;
- its imporant to note that traumatic, inflammatory, and neoplastic disorders will have similar appearances;
- some of lesions will have an increased signal intensity on T2 sequences (primary tumor, metastatic lesions, and infections) while others lesions will have low signal on T2 (leukemia, lymphoma);
- osteonecrosis has consistent decreased signal intensity on T1 images as compared to high signal of normal marrow (see MRI of AVN of femoral head)