Home » Arthritis » Diflunisal/Dolobid Diflunisal/Dolobid July 22, 2020 by Data Trace Editor - NSAIA; - for musculoskeletal pain and osteoarthritis; - adult dose: 500 mg every 8 to 12 hours (500-1500 mg/day PO divided doses); - ? may increase PT; - w/ impaired renal or hepatic function, cut dose in half; - Tabs: 250, 500 mg