The Hip book

Amphotericin B/Fungizone

 – for severe systemic fungal infections;  – dose: 0.25mg/kg IV over 6hrs initially (infusion .1mg/ml);  – gradually increase dose as tolerated up to 1-1.5mg/kg/24hrIV over 6hr;  – note hypersensitivity, caution with nephrotoxic/antineoplastic agents;  – monitor blood, liver, and renal function,  – discontinue therapy if BUN >40mg/dl, Creatinine >3.0mg/dl, or if liver function test abnormalities are … Read more